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Cajun Chicken Pasta Bake: The Ultimate Comfort Food Recipe


  • Total Time: 50 minutes
  • Yield: 6-8 servings 1x

Description

Creamy, cheesy Cajun Chicken Pasta Bake! Comforting and delicious, perfect for weeknights or potlucks.


Ingredients

Scale
  • 2 large boneless, skinless chicken breasts, cut into 1-inch cubes
  • 2 tablespoons olive oil
  • 2 tablespoons Cajun seasoning (store-bought or homemade)
  • 1 teaspoon garlic powder
  • 1/2 teaspoon onion powder
  • 1/4 teaspoon cayenne pepper (optional, for extra heat)
  • Salt and freshly ground black pepper to taste
  • 1 pound pasta (penne, rotini, or farfalle work well)
  • 8 ounces cream cheese, softened
  • 1 cup heavy cream
  • 1 cup milk
  • 1 cup shredded Monterey Jack cheese
  • 1/2 cup shredded Parmesan cheese
  • 1/2 cup chopped green bell pepper
  • 1/2 cup chopped red bell pepper
  • 1/2 cup chopped yellow onion
  • 2 cloves garlic, minced
  • 1 tablespoon butter
  • 1 teaspoon Cajun seasoning (or more, to taste)
  • 1/2 teaspoon garlic powder
  • 1/4 teaspoon onion powder
  • Salt and freshly ground black pepper to taste
  • 2 tablespoons chopped fresh parsley, for garnish (optional)

Instructions

  1. In a medium bowl, combine the cubed chicken breasts, olive oil, Cajun seasoning, garlic powder, onion powder, cayenne pepper (if using), salt, and pepper. Toss well to coat.
  2. Heat a large skillet over medium-high heat. Add the seasoned chicken in a single layer (cook in batches if needed).
  3. Cook the chicken for 5-7 minutes, or until cooked through and no longer pink inside, stirring occasionally. Remove from skillet and set aside.
  4. While the chicken is cooking, bring a large pot of salted water to a boil. Add the pasta and cook according to package directions until al dente. Drain well and set aside.
  5. In the same skillet you used for the chicken, melt the butter over medium heat. Add the chopped green bell pepper, red bell pepper, and yellow onion. Cook for 5-7 minutes, or until softened.
  6. Add the minced garlic and cook for another minute, or until fragrant.
  7. Reduce the heat to low. Add the softened cream cheese and stir until melted and smooth.
  8. Gradually pour in the heavy cream and milk, stirring constantly to prevent lumps.
  9. Add the Monterey Jack cheese and Parmesan cheese and stir until melted and the sauce is smooth and creamy.
  10. Stir in the Cajun seasoning, garlic powder, onion powder, salt, and pepper. Taste and adjust seasonings as needed.
  11. Preheat your oven to 350°F (175°C).
  12. Add the cooked pasta and cooked chicken to the skillet with the sauce. Toss well to coat.
  13. Pour the pasta mixture into a greased 9×13 inch baking dish. Spread evenly.
  14. Sprinkle the remaining Monterey Jack cheese and Parmesan cheese over the top.
  15. Bake in the preheated oven for 20-25 minutes, or until the cheese is melted, bubbly, and lightly golden brown.
  16. Remove from the oven and let cool for a few minutes before serving.
  17. Garnish with chopped fresh parsley, if desired.

Notes

  • Spice Level: Adjust the amount of Cajun seasoning and cayenne pepper to your liking.
  • Cheese: Experiment with different cheeses like cheddar, Colby Jack, or Pepper Jack.
  • Vegetables: Add mushrooms, spinach, or sun-dried tomatoes. Sauté with the bell peppers and onion.
  • Meat: Use sausage, shrimp, or crawfish instead of chicken. Cook before adding.
  • Make-Ahead: Assemble ahead of time and refrigerate for up to 24 hours. Add extra baking time when ready to bake.
  • Cream Cheese Alternative: Use mascarpone or ricotta cheese.
  • Gluten-Free: Use gluten-free pasta.
  • Dairy-Free: Use dairy-free cream cheese, coconut cream, almond/oat milk, and dairy-free cheese.
  • Breadcrumb Topping: Mix 1/2 cup breadcrumbs with 2 tablespoons melted butter and sprinkle over cheese before baking.
  • Rotisserie Chicken: Use pre-cooked rotisserie chicken to save time.
  • Prep Time: 20 minutes
  • Cook Time: 25 minutes